FIND stem cells created a "by-pass the damaged arteries(Foto: Archivo ELUNIVERSAL )
A study led by a Spanish hospital has made stem cells from bone marrow to produce blood vessels in diabetic lower extremity arteries were badly damaged by the disease, which have improved circulation and away the risk of amputation.
In this phase II trial, one of the pioneers in national and international level and whose results were presented today. Sixty patients participated in five Spanish hospitals.
The aim of the study, according to the cardiovascular surgeon Antonio Chacón, is to avoid amputation, between 15 000 and 20 000 amputations per year in Spain by this disease, thanks to new vessels bring more blood to the leg and found that it creates "by-pass "of the damaged arteries.
The aim of the study, according to the cardiovascular surgeon Antonio Chacón, is to avoid amputation, between 15 000 and 20 000 amputations per year in Spain by this disease, thanks to new vessels bring more blood to the leg and found that it creates "by-pass "of the damaged arteries.
The sixty patients had severe peripheral vascular disease and had no alternative treatment other than the cell therapy, which has not generated any of them a serious adverse reaction and the majority seem to experience an improvement in their prognosis and quality of life.
The process for the administration of cell therapy begins with an operation that does not exceed 30 minutes in which the patient is given local anesthesia to extract stem cells from their bone marrow.
Later in the laboratory are separated bone marrow cells that are necessary and are prepared to infuse, hours later, in the arteries below the knee by using catheters.
The director of Cell Therapy Laboratory, Concepción Herrera, said that the study involved four groups of patients who were randomly has provided 100 million stem cells, 500 million, 1,000 million or any amount to see if the number of cells is applied affects the results.
Patients, most of which have already been evaluated at six months and one year, have presented an evolution "excellent and favorable" since the first day due to collateral circulation is increased and generate new arteries that are not temporary but permanent.
The director of Cell Therapy Laboratory, Concepción Herrera, said that the study involved four groups of patients who were randomly has provided 100 million stem cells, 500 million, 1,000 million or any amount to see if the number of cells is applied affects the results.
Patients, most of which have already been evaluated at six months and one year, have presented an evolution "excellent and favorable" since the first day due to collateral circulation is increased and generate new arteries that are not temporary but permanent.
No hay comentarios:
Publicar un comentario